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Science Signaling Science Signaling
The Leading Journal for Cell Signaling
11/08/2012

Dear Dr. {Last name},

I am very pleased to announce that the Impact Factor of Science Signaling has increased to 7.50. Science Signaling publishes Research Articles and Research Resources in the multidisciplinary field of cell signaling. Research Articles report hypothesis-driven research related to the molecular mechanisms through which cells respond to changes in their external or internal environments; whereas Research Resources may describe nonhypothesis-driven research, including the presentation of new validated tools or techniques or validated databases or data sets relevant to cellular regulation.

Consider submitting your next manuscript to Science Signaling.

Sample journal content:

Access to these articles is free with registration:

Wnt/β-Catenin Signaling and AXIN1 Regulate Apoptosis Triggered by Inhibition of the Mutant Kinase BRAFV600E in Human Melanoma
T. L. Biechele, R. M. Kulikauskas, R. A. Toroni, O. M. Lucero, R. D. Swift, R. G. James, N. C. Robin, D. W. Dawson, R. T. Moon, A. J. Chien  (2012) – Free access until 8 December 2012

Estrogen Regulates Tumor Growth Through a Nonclassical Pathway that Includes the Transcription Factors ERβ and KLF5
Y. Nakajima, K. Akaogi, T. Suzuki, A. Osakabe, C. Yamaguchi, N. Sunahara, J. Ishida, K. Kako, S. Ogawa, T. Fujimura, Y. Homma, A. Fukamizu, A. Murayama, K. Kimura, S. Inoue, J. Yanagisawa (2011)

Identification of the miR-106b~25 MicroRNA Cluster as a Proto-Oncogenic PTEN-Targeting Intron That Cooperates with Its Host Gene MCM7 in Transformation
L. Poliseno, L. Salmena, L. Riccardi, A. Fornari, M. S. Song, R. M. Hobbs, P. Sportoletti, S. Varmeh, A. Egia, G. Fedele, L. Rameh, M. Loda, P. P. Pandolfi (2010)

Tyrosine Phosphorylation Inhibits PKM2 to Promote the Warburg Effect and Tumor Growth
T. Hitosugi, S. Kang, M. G. Vander Heiden, T.-W. Chung, S. Elf, K. Lythgoe, S. Dong, S. Lonial, X. Wang, G. Z. Chen, J. Xie, T.-L. Gu, R. D. Polakiewicz, J. L. Roesel, T. J. Boggon, F. R. Khuri, D. G. Gilliland, L. C. Cantley, J. Kaufman, J. Chen (2009)

Journal scope:

Appropriate topics include any analysis of the mechanisms by which cellular functions are regulated in response to external or internal cues in both eukaryotic and prokaryotic cells. The journal crosses the boundaries of traditional research areas, such as Cancer Biology, Cell Cycle Regulation, Cell Biology, Biochemistry, Development, Microbiology, Molecular Biology, Immunology, Neuroscience, Physiology and Medicine, Pharmacology, and Plant Biology. Visit our website for additional information including our Editorial and peer-review process.

We look forward to receiving your manuscript describing an advance in cellular regulation.

Best wishes,

Nancy R. Gough, Ph.D.
Editor, Science Signaling


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