In this week's issue:
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| Special
Section |
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Introduction
to Special Issue
INTRODUCTION
Kristen
Mueller
Special
Issue Review
Adriano
Aguzzi et al.
Filip
K. Swirski and Matthias
Nahrendorf
Ira
Tabas and Christopher K. Glass
Justin
I. Odegaard and Ajay Chawla
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| Research
Summaries |
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Editor summaries of this
week's papers.
Highlights of the recent
literature.
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| Editorial
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| News of
The Week |
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In science news around the
world this week, 74 Chinese
cities began measuring
concentrations of harmful
particulate matter, a Chinese
government regulation
toughening penalties for
academic fraud took effect,
the company that owned the Deepwater
Horizon agreed to pay
$1.4 billion, the U.S. Supreme
Court has rejected a case
challenging government-funded
research on human embryonic
stem cells, and more.
Carl Woese, who
revolutionized microbiology
through his studies of
single-celled microbes called
archaea, and Rita
Levi-Montalcini, who was
awarded the Nobel Prize in
physiology or medicine for her
discovery of nerve growth
factor, have died. The U.S.
National Academy of
Engineering announced that it
will honor three teams for
notable achievements in
telecommunications,
bioengineering, and
engineering education.
Researchers discovered that
though the pale wrinkles that
adorn fingertips after an
extended soaking may be
unsightly, they help us get a
stronger grip on slippery
objects. In other news, a
close look at fossils of a
group of bipedal dinosaurs
suggests that many of them
shook their muscular,
feather-adorned tails to gain
attention during courtship.
And this week's ScienceLIVE
will look at some provocative
new insights into tackling
global warming, while this
week's by the numbers features
carbon dioxide emissions of
the world's telecommunications
infrastructure and the planets
in the Milky Way galaxy.
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| News
& Analysis |
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U.S.
BUDGET
Jeffrey
Mervis
The battle over the fiscal
cliff is far from over for
U.S. scientists.
GLOBAL
WARMING
Eli
Kintisch
A provocative new study looks
at the influential 2004 paper
that introduced the concept of
climate "wedges"—and the
sobering question of what it
may take to stabilize and then
phase-out emissions of global
warming gases.
INFECTIOUS
DISEASE
Jon
Cohen
On New Year's Eve, the U.S.
Food and Drug Administration
approved the first new
tuberculosis drug in more than
40 years.
CHINA
Mara
Hvistendahl
Researchers have attempted to
measure the degree to which
the one-child policy has
shaped the personalities of
Chinese 20- and 30-somethings.
IMAGE
MANIPULATION
Jennifer
Couzin-Frankel
A highly respected
mitochondrial biologist is
behind an acerbic blog
dedicated to unmasking
scientific wrongdoing.
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| News
Focus |
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Jocelyn
Kaiser
Having spent about $1 billion
over the past decade, a U.S.
study of environmental
influences on children's
health is still trying to
define its methods. Critics
say it has gone astray;
advocates say it is on track
at last.
CONSULTING
Jeffrey
Mervis
What every academic and
clinical researcher should
know before signing up with an
expert network firm and
interacting with its clients.
CONSULTING
Jeffrey
Mervis
What happened when a positive
drug report led to a declining
stock price? How one expert's
opinion made an impact
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| Letters
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Jeffrey
S. Flier
S.
L. Chown
Hong
Yang et al.
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| Books et
al. |
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ECOLOGY
Rolf
O. Peterson
Contesting the generally
accepted models of
predator-prey dynamics, Arditi
and Ginzburg marshal evidence
for their ratio-dependent
alternative.
HUMAN
DEVELOPMENT
Johan
J. Bolhuis
Rejecting dichotomous views
of development, Goldhaber
suggests that a synthesis of
evolutionary psychology and
developmental systems theory
will resolve long-standing
debates.
A listing of books received at
Science during the
week ending 04 January 2013.
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| Policy
Forum |
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RESEARCH
ETHICS
R.
Benjamin Shapiro and Pilar N.
Ossorio
How should research studying
adolescent players of online
educational games be conducted
responsibly?
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| Perspectives
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BIOCHEMISTRY
John
R. Helliwell
Femtosecond pulses from an
x-ray laser are used to solve
the room-temperature structure
of a protein. [Also see Report
by Redecke et
al.]
BIOMEDICINE
Anthony
W. Ferrante
JNK activity in adipose
macrophages promotes
inflammation and insulin
resistance in mouse models of
obesity. [Also see Report by Han et
al.]
PHYSIOLOGY
Paolo
Sassone-Corsi
Nutrition, energy metabolism,
and the plasticity of gene
expression are linked through
the action of epigenetic
modifiers that are modulated
by cellular metabolites. [Also
see Reports by Shimazu et
al. and Shyh-Chang et
al.]
MATERIALS
SCIENCE
Hyoki
Kim and Sunghoon Kwon
Films swollen by wet surfaces
curl up and store mechanical
energy that can be converted
into electricity for powering
small devices. [Also see
Report by Ma et
al.]
NEUROSCIENCE
Markus
Knaden and Bill S. Hansson
Hawk moths are specialized to
recognize the odors from
specific plants but can learn
to recognize and follow other
plant odors. [Also see Report
by Riffell et
al.]
NEUROSCIENCE
Antje
Grosche and Andreas Reichenbach
A change in glutamate receptor
expression in adult glial
cells advances the current
model of how glia regulate
neuronal activity. [Also see
Report by Sun et
al.]
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| Reports
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M.
Hatridge et al.
The evolution of a quantum
system can be tracked via a
series of partial measurements
that leave the system in a
pure state.
Natnael
Behabtu et al.
Exceptional carbon nanotube
fibers are produced by a wet
spinning process using longer
nanotubes as feedstock.
Mingming
Ma et al.
Polymer actuators are
manipulated by changing
hydration conditions and show
strong contractile forces.
[Also see Perspective by Kim and Kwon]
Bartosz
Lewandowski et al.
A macrocycle threaded on a
rod can catalytically insert
several amino acids placed
along its path into a peptide
chain.
Yoko
Sakata et al.
A porous material retains its
framework shape after guest
molecules desorb if its
crystallites are sufficiently
small.
Wei
Sun et al.
The expression of
metabotropic glutamate
receptors in brain astrocytes
is down-regulated in early
postnatal development. [Also
see Perspective by Grosche and
Reichenbach]
Jeffrey
A. Riffell et al.
Hawkmoths supplement their
innate repertoire of
attractive flower odors by
learning new ones via an
octopamine pathway. [Also see
Perspective by Knaden and
Hansson]
Thomas
Di Meglio et al.
During brain development,
epigenetic mechanisms allow
tangentially migrating neurons
to retain topographical
organization.
Christopher
H. Martin and Peter C.
Wainwright
Increased competition drives
phenotypic adaptive
specialization within Cyprinodon
pupfishes in lakes in the
Bahamas.
Tadahiro
Shimazu et al.
Ketone bodies, metabolites
that accumulate during
fasting, change gene
expression by inhibiting
histone deacetylases. [Also
see Perspective by Sassone-Corsi]
Laurent
Acquaviva et al.
A protein involved in histone
methylation targets the
meiotic recombination
machinery to chromatin.
Myoung
Sook Han et al.
A kinase in macrophages is
required for high-fat
diet–induced metabolic changes
and inflammation. [Also see
Perspective by Ferrante Jr.]
Ng
Shyh-Chang et al.
Unusual threonine metabolism
in mouse stem cells influences
genetic reprogramming via
altered histone methylation.
[Also see Perspective by Sassone-Corsi]
Lars
Redecke et al.
In vivo crystallization and
serial femtosecond
crystallography reveal the
structure of a sleeping
sickness parasite protease.
[Also see Perspective by Helliwell]
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